Publications of the Division Infections and Cancer Epidemiology (F020)

• Publications in 2019
• Publications in 2020
• Publications in 2021
• Publications in 2022
• Publications in 2023

Members of the division have authored more than 350 international, peer-reviewed publications (for a full list, please see PubMed).

1. Busch CJ, Hoffmann AS, Viarisio D, Becker BT, Rieckmann T,..., Burandt E, Lang Kuhs K, Pawlita M, Waterboer T*, Brenner N*. Detection of stage I HPV-driven oropharyngeal cancer in asymptomatic individuals in the Hamburg City Health Study using HPV16 E6 serology - A proof-of-concept study. EClinicalMedicine. 2022 Sep 17;53:101659
2. Stich M, Benning L, Speer C, Garbade SF, Bartenschlager M,..., Waterboer T, Hoffmann GF, Kräusslich HG, Müller B, Bartenschlager R, Tönshoff B. Waning Immunity 14 Months After SARS-CoV-2 Infection. Pediatrics. 2022 Nov 1;150(5):e2022057151
3. Robbins HA, Ferreiro-Iglesias A, Waterboer T, Brenner N, Nygard M,..., Huang WY, Freedman ND, Kreimer AR, Johansson M, Brennan P. Absolute Risk of Oropharyngeal Cancer After an HPV16-E6 Serology Test and Potential Implications for Screening: Results From the Human Papillomavirus Cancer Cohort Consortium. J Clin Oncol. 2022 Nov 1;40(31):3613-3622
4. Mentzer AJ, Brenner N, Allen N, Littlejohns TJ, Chong AY,..., McVean G; UKB Infection Advisory Board, Collins R, Hill AVS, Waterboer T. Identification of host-pathogen-disease relationships using a scalable multiplex serology platform in UK Biobank. Nat Commun. 2022 Apr 5;13(1):1818
5. Butt J, Lehtinen M, Öhman H, Waterboer T, Epplein M. Association of Helicobacter pylori and autoimmune gastritis with stomach cancer in a cohort of young Finnish women. Gastroenterology. 2022 Jul;163(1):305-307.e4
6. Artola-Borán M, Fallegger A, Priola M, Jeske R, Waterboer T,..., Levesque MP, Yousefi S, Simon HU, Cheng PF, Müller A. Mycobacterial infection aggravates Helicobacter pylori-induced gastric preneoplastic pathology by redirection of de novo induced Treg cells. Cell Rep. 2022 Feb 8;38(6):110359
7. Yang L, Kartsonaki C, Yao P, de Martel C, Plummer M,..., Waterboer T, Clifford GM, Franceschi S, Peto R, Hill M, Li L, Millwood IY, Chen Z; China Kadoorie Biobank Collaborative Group. The relative and attributable risks of cardia and non-cardia gastric cancer associated with Helicobacter pylori infection in China: a case-cohort study. Lancet Public Health. 2021 Dec;6(12):e888-e896
8. Stich M, Elling R, Renk H, Janda A, Garbade SF,..., Waterboer T, Franz AR, Hoffmann GF, Engel C, Debatin KM, Tönshoff B, Henneke P. Transmission of Severe Acute Respiratory Syndrome Coronavirus 2 in Households with Children, Southwest Germany, May-August 2020. Emerg Infect Dis. 2021 Dec;27(12):3009-3019
9. Ferreiro-Iglesias A, McKay JD, Brenner N, Virani S, Lesseur C,..., Agudo A, Znaor A, Amos CI, Waterboer T*, Brennan P*. Germline determinants of humoral immune response to HPV-16 protect against oropharyngeal cancer. Nat Commun. 2021 Oct 12;12(1):5945
10. Seeßle J, Waterboer T, Hippchen T, Simon J, Kirchner M, Lim A, Müller B, Merle U. Persistent symptoms in adult patients one year after COVID-19: a prospective cohort study. Clin Infect Dis. 2022 Apr 9;74(7):1191-1198
11. Béziat V, Rapaport F, Hu J, Titeux M, Bonnet des Claustres M,..., Waterboer T, Langlais D, Doorbar J, Hovnanian A, Christensen N, Bossuyt X, Shahrooei M, Casanova JL. Humans with inherited T cell CD28 deficiency are susceptible to skin papillomaviruses but are otherwise healthy. Cell. 2021 Jul 8;184(14):3812-3828.e30
12. Mariz FC, Gray P, Bender N, Eriksson T, Kann H,..., Surcel HM, Waterboer T, Müller M, Pawlita M, Lehtinen M. Sustainability of neutralising antibodies induced by bivalent or quadrivalent HPV vaccines and correlation with efficacy: a combined follow-up analysis of data from two randomised, double-blind, multicentre, phase 3 trials. Lancet Infect Dis. 2021 Oct;21(10):1458-1468
13. Butt J, Jenab M, Werner J, Fedirko V, Weiderpass E,..., Freisling H, Zouiouich S, Aglago E, Waterboer T, Hughes DJ. Association of Pre-diagnostic Antibody Responses to Escherichia coli and Bacteroides fragilis Toxin Proteins with Colorectal Cancer in a European Cohort. Gut Microbes. 2021 Jan-Dec;13(1):1-14
14. Varga MG, Wood CR, Butt J, Ryan ME, You WC, Pan K, Waterboer T, Epplein M, Shaffer CL. Immunostimulatory membrane proteins potentiate H. pylori-induced carcinogenesis by enabling CagA translocation. Gut Microbes. 2021 Jan-Dec;13(1):1-13
15. Brenner N, Mentzer AJ, Hill M, Almond R, Allen N, Pawlita M, Waterboer T. Characterization of human papillomavirus (HPV) 16 E6 seropositive individuals without HPV-associated malignancies after 10 years of follow-up in the UK Biobank. EBioMedicine. 2020 Dec;62:103123
16. Waterboer T, Brenner N, Gallagher R, Hillman RJ, Jin F, Grulich A, Poynten IM. Early Detection of Human Papillomavirus-Driven Oropharyngeal Cancer Using Serology From the Study of Prevention of Anal Cancer. JAMA Oncol. 2020 Oct 1;6(11):1806-8
17. Simon J, Schroeder L, Ingarfield K, Diehl S, Werner J, Brenner N, Liu Z, Pawlita M, Pring M, Butt J, Ness A, Waterboer T. Epstein-Barr virus and human papillomavirus serum antibodies define the viral status of nasopharyngeal carcinoma in a low endemic country. Int J Cancer. 2020 Jul 15;147(2):461-471
18. Simon J, Liu Z, Brenner N, Yu KJ, Hsu WL, Wang CP, Chien YC, Coghill AE, Chen CJ, Butt J, Proietti C, Doolan DL, Hildesheim A, Waterboer T. Validation of an Epstein-Barr Virus Antibody Risk Stratification Signature for Nasopharyngeal Carcinoma by Use of Multiplex Serology. J Clin Microbiol. 2020 Apr 23;58(5):e00077-20
19. Combes JD, Clifford GM, Günthard HF, Hauser C, Darling KEA, Valladares P, Battegay M, Waldeck F, Bernasconi E, Bertisch B, Hirsch HH, Brenner N, Waterboer T, Scherrer AU; Swiss HIV Cohort Study. Antibodies against HPV16E6 oncoprotein in the Swiss HIV cohort study: Kinetics and anal cancer risk prediction. Int J Cancer. 2020 Aug 1;147(3):757-765
20. Tengvall K, Huang J, Hellström C, Kammer P, Biström M,..., Sundström P, Nilsson P, Waterboer T, Olsson T, Kockum I. Molecular mimicry between Anoctamin 2 and Epstein-Barr virus nuclear antigen 1 associates with multiple sclerosis risk. Proc Natl Acad Sci U S A. 2019 Aug 20;116(34):16955-16960
21. Kreimer AR, Ferreiro-Iglesias A, Nygard M, Bender N, Schroeder L,..., Huang WY, Freedman ND, Brennan P, Waterboer T*, Johansson M*. Timing of HPV16-E6 antibody seroconversion before OPSCC: findings from the HPVC3 consortium. Ann Oncol. 2019 Aug 1;30(8):1335-1343
22. Butt J, Varga MG, Blot WJ, Teras L, Visvanathan K,..., Berndt S, Hildesheim A, Waterboer T, Pawlita M, Epplein M. Serological response to Helicobacter pylori proteins associate with risk of colorectal cancer among diverse populations in the United States. Gastroenterology. 2019 Jan;156(1):175-186
23. Marra E, Siegenbeek van Heukelom ML, Leeman A, Waterboer T,..., van der Weele P, Quint W, Prins JM, de Vries HJC, Schim van der Loeff MF. Virological and serological predictors of anal high-grade squamous intraepithelial lesions among HIV-positive men who have sex with men. Clin Infect Dis. 2019 Apr 8;68(8):1377-1387
24. Woodhall SC, Gorwitz RJ, Migchelsen SJ, Gottlieb SL, Horner PJ,..., Waterboer T, Martin DL, Huston WM, Gaydos CA, Deal C, Unemo M, Dunbar JK, Bernstein K. Advancing the public health applications of Chlamydia trachomatis serology. Lancet Infect Dis. 2018 Dec;18(12):e399-e407
25. Trabert B, Waterboer T, Idahl A, Brenner N, Brinton LA,..., Sherman ME, Wills GS, Woodhall SC, Pawlita M, Wentzensen N. Antibodies Against Chlamydia trachomatis and Ovarian Cancer Risk in Two Independent Populations. J Natl Cancer Inst. 2019 Feb 1;111(2):129-136
26. Hufnagel K, Lueong S, Willhauck-Fleckenstein M, Hotz-Wagenblatt A, Miao B, Bauer A, Michel A, Butt J, Pawlita M, Hoheisel JD, Waterboer T. Immunoprofiling of Chlamydia trachomatis using whole-proteome microarrays generated by on-chip in situ expression. Sci Rep. 2018 May 14;8(1):7503
27. Kreimer AR, Shiels MS, Fakhry C, Johansson M, Pawlita M, Brennan P, Hildesheim A, Waterboer T. Screening for human papillomavirus-driven oropharyngeal cancer: Considerations for feasibility and strategies for research. Cancer. 2018 May 1;124(9):1859-1866
28. Butt J, Jenab M, Willhauck-Fleckenstein M, Michel A, Pawlita M,..., Riboli E, Tsilidis K, Aune D, Waterboer T*, Hughes DJ*. Prospective evaluation of antibody response to Streptococcus gallolyticus and risk of colorectal cancer. Int J Cancer. 2018 Jul 15;143(2):245-252
29. Kreimer AR, Johansson M, Yanik EL, Katki HA, Check DP,..., Purdue MP, Michel A, Pawlita M, Brennan P, Waterboer T. Kinetics of the Human Papillomavirus Type 16 E6 Antibody Response Prior to Oropharyngeal Cancer. J Natl Cancer Inst. 2017 Aug 1;109(8)
30. Ayoglu B, Mitsios N, Kockum I, Khademi M, Zandian A,..., Waterboer T, Alfredsson L, Mulder J, Schwenk JM, Olsson T, Nilsson P. Anoctamin 2 identified as an autoimmune target in multiple sclerosis. Proc Natl Acad Sci U S A. 2016 Feb 23;113(8):2188-93
31. Sankaranarayanan R, Prabhu PR, Pawlita M, Gheit T, Bhatla N,..., Waterboer T, Müller M, Sehr P, Hingmire S, Kriplani A, Mishra G, Pimple S, Jadhav R, Sauvaget C, Tommasino M, Pillai MR; Indian HPV vaccine study group. Immunogenicity and HPV infection after one, two, and three doses of quadrivalent HPV vaccine in girls in India: a multicentre prospective cohort study. Lancet Oncol. 2016 Jan;17(1):67-77
32. Kreimer AR, Brennan P, Lang Kuhs KA, Waterboer T, Clifford G,..., Travis RC, Quirós JR, Weiderpass E, Pawlita M, Johansson M. Human Papillomavirus Antibodies and Future Risk of Anogenital Cancer: A Nested Case-Control Study in the European Prospective Investigation Into Cancer and Nutrition Study. J Clin Oncol. 2015 Mar 10;33(8):877-84
33. Kreimer AR, Johansson M, Waterboer T, Kaaks R, Chang-Claude J,..., Riboli E, Hildesheim A, Boeing H, Pawlita M, Brennan P. Evaluation of human papillomavirus antibodies and risk of subsequent head and neck cancer. J Clin Oncol.2013 Jul 20;31(21):2708-15